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Clinical Epidemiology & Evidence-Based Medicine
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Clinical Epidemiology & Evidence-Based Medicine
Fundamental Principles of Clinical Reasoning & Research



October 2001 | 320 pages | SAGE Publications, Inc
Clinical Epidemiology & Evidence-based Medicine is a resource for all health-care workers involved in applying evidence to the care of their patients.

Using clinical examples and citing liberally from the peer-reviewed literature,

the book shows how statistical principles can improve medical decisions.

This work shows how probability, risk and alternatives are fundamental considerations in all clinical decisions, and demonstrates the intuitive basis for using clinical epidemiolgy as a science underlying medical decisions. This book is a useful reference tool that will assist the clinician to better access, interpret, and apply evidence to patient care as well as better understand and control the process of medical decision making.

 
SECTION I: PRINCIPLES OF CLINICAL REASONING
 
Of Patients & Populations: Population-Based Data in Clinical Practice
 
Test Performance: Disease Probability, Test Interpretation & Diagnosis
 
Quantitative Aspects of Clinical Thinking: Predictive Values and Bays' Theorem
 
Fundamentals of Screening: The Art and Science of Looking for Trouble
 
Measuring and Conveying Risk
 
SECTION II: PRINCIPLES OF CLINICAL RESEARCH
 
Hypothesis Testing 1: Principles
 
Hypothesis Testing 2: Mechanics
 
Study Design
 
Interpreting Statistics in the Medical Literature
 
SECTION III: FROM RESEARCH TO REASONING: THE APPLICATION OF EVIDENCE IN CLINICAL PRACTICE
 
Decision Analysis
 
Diagnosis
 
Management
 
APPENDICES

"The presentation is consistently excellent. One, the writing is lucid and organized in a way that should be very natural for the clinical reader. Two, the text requires no background in mathematics and uses a minimum of symbols. And, three, the methodological concepts and clinical issues are well integrated through a number of carefully prepared and comprehensive examples." 

Greg Samsa
Associate Director, Duke Center for Clinical Health Policy Research

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