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Epigenetics Insights

Epigenetics Insights

Christian Bronner University of Strasbourg, France
Executive Editor
Barbara Rattner, PhD SAGE Publishing, Thousand Oaks, CA USA

eISSN: 25168657 | ISSN: 25168657 | Current volume: 10 | Current issue: 1

Journal Highlights

  • Indexed using PubMed Central (PMC), DOAJ, ESCI, and Scopus
  • Published since 2008
  • Publication is subject to payment of an article processing charge (APC)

Epigenetics Insights is an open access, peer-reviewed international journal focusing on all aspects of epigenetics, including technical and ethical issues. Please see the Aims and Scope tab for further information.

This journal is a member of the Committee on Publication Ethics (COPE).

Submission Information

Submit your manuscript here.
Please see the Submission Guidelines tab for more information on how to submit your article to the journal.

Open access article processing charge (APC) information

Publication in the journal is subject to payment of an article processing charge (APC). The APC serves to support the journal and ensures that articles are freely accessible online in perpetuity under a Creative Commons license.

The APC for this journal is $1500 USD.

The article processing charge (APC) is payable only if your article is accepted after peer review, before it is published. The APC is subject to taxes where applicable. Tax-exempt status can be indicated by providing appropriate registration numbers when payment is requested. Please see further details here.


Please direct any queries to

Other Information

This journal was previous known as Genetics & Epigenetics.

Epigenetics Insights (previously known as Genetics & Epigenetics) is an open access, peer-reviewed journal that covers all aspects of epigenetics, including technical and ethical issues. Epigenetics Insights aims to offer a channel for the presentation and discussion of the role of epigenetics processes (including, but not limited to, DNA methylation, gene silencing, imprinting, nuclear organization and reprogramming, histone modification, chromatin remodeling and dynamics, non-coding RNAs, and dosage compensation) in all areas of biology.

The journal is now organized into topical sections, with dedicated section editors overseeing the peer review process and guaranteeing rapid while rigorous peer review. Manuscripts are reviewed by experts in the field. Our goal is to return reviews and first decisions within 30 days of submission.

Epigenetics Insights Topical Sections
We welcome the submission of original manuscripts in the following areas:

  • Cancer epigenetics
  • Cardiovascular epigenetics
  • Developmental & reproductive epigenetics
  • Epigenetic disease model organisms
  • Environmental & nutritional epigenetics
  • Epigenetic clinical trials
  • Epigenetic therapies & diagnostics
  • Epigenetic tools & techniques
  • Epigenetics of aging
  • Epigenetics of allergy, immunology, and infectious disease
  • Epigenetics of metabolic disease and endocrinology
  • Neuroepigenetics
  • Plant epigenetics

Manuscript Submission


Executive Editor
Barbara Rattner, PhD SAGE Publishing, Thousand Oaks, CA USA
Editor in Chief
Christian Bronner University of Strasbourg, France
Deputy Editor in Chief
Ulrich Mahlknecht Saarland University, Germany
Section Editors - Developmental and Reproductive Epigenetics
Rocio M. Rivera University of Missouri, USA
Section Editors - Cancer Epigenetics
Emily Bernstein Icahn School of Medicine at Mount Sinai, USA
Section Editors - Environmental and Nutritional Epigenetics
Dana Dolinoy University of Michigan, USA
Section Editors - Epigenetics of Aging
Rocio M. Rivera University of Missouri, USA
Section Editors - Epigenetics of Metabolic Disease and Endocrinology
Jason Locasale Duke University, USA
Editorial Board
Mahmoud Alhosin King Abdulaziz University, Saudi Arabia
Paula Desplats University of California, San Diego, USA
Richard J. Festenstein Imperial College London, UK
Antonio Giordano Temple University, USA
Shiv Grewal National Cancer Institute, USA
Zong Sheng Guo University of Pittsburgh Cancer Institute, USA
Karmella A. Haynes Arizona State University, USA
Steven Jacobsen University of California, Los Angeles, USA
Albert Jeltsch Universität Stuttgart, Germany
James T. Kadonaga University of California, San Diego, USA
Ahmad (Mo) Khalil Boston University, USA
Alberto R. Kornblihtt University of Buenos Aires, Argentina
Congjun Li United States Department of Agriculture, USA
Ming D. Li University of Virginia, USA
Xiu-Qing Li Agriculture and Agri-Food Canada, Canada
Chunyun Liu University of Illinois at Chicago, USA
Sylviane Muller Centre Nationale de Recherche Scientifique, France
Susan Murphy Duke University Medical Center, USA
Delvac Oceandy University of Manchester, UK
Ana Pombo Max-Delbrück-Centrum für Molekulare Medizin, Germany
Kaushik Ragunathan University of Michigan Medical School, USA
Mangalathu S. Rajeevan Centers for Disease Control and Prevention, USA
Félix Recillas-Targa Universidad Nacional Autónoma de México, México
Martin Sebastian Staege Martin-Luther University, Germany
Winston Timp Johns Hopkins University, USA
Ming T. Tsuang Harvard Medical School, USA
Steve Walker Wake Forest Institute for Regenerative Medicine, USA
  • Clarivate Analytics: Emerging Sources Citation Index (ESCI)
  • Directory of Open Access Journals (DOAJ)
  • PubMed Central (PMC)
  • Scopus
  • This Journal is a member of the Committee on Publication Ethics. This Journal recommends that authors follow the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals formulated by the International Committee of Medical Journal Editors (ICMJE).

    Only manuscripts of sufficient quality that meet the aims and scope of Epigenetic Insights will be reviewed.

    As part of the submission process you will be required to warrant that you are submitting your original work, that you have the rights in the work, that you are submitting the work for first publication in the Journal and that it is not being considered for publication elsewhere and has not already been published elsewhere, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you.

    Please read the complete guidelines below before you upload your mauscript.  



    1. Open Access

    2. Article Processing Charge (APC)

    3. What Do We Publish?
         3.1 Aims & Scope
         3.2 Article Types
         3.3 Writing Your paper
                3.3.1 Making Your Article Discoverable

    4. Editorial Policies
         4.1 Peer Review Policy
         4.2 Authorship
         4.3 Acknowledgements
              4.3.1 Writing Assistance
         4.4 Funding
         4.5 Declaration of Conflicting Interests
         4.6 Research Ethics and Patient Consent
         4.7 Clinical Trials
         4.8 Reporting Guidelines

    5. Publishing Policies
         5.1 Publication Ethics
               5.1.1 Plagiarism
               5.1.2 Prior Publication
         5.2 Contributor’s Publishing Agreement    

    6. Preparing Your Manuscript
         6.1 Word Processing Formats
         6.2 Artwork, Figures and other Graphics
         6.3 Supplemental Material
         6.4 Reference Syle
         6.5 English Language Editing Services

    7. Submitting your Manuscript
         7.1 How to Submit your Manuscript
         7.2 Title, Keywords and Abstract
         7.3 Information Required for Completing your Submission
         7.4 ORCID
         7.5 Permissions

    8. On Acceptance and Publication
         8.1 SAGE Production
         8.2 Online Publication
         8.3 Promoting Your Article

    9. Further Information


    1. Open Access

    Epigenetic Insights is an open access, peer-reviewed journal. Each article accepted by peer review is made freely available online immediately upon publication, is published under a Creative Commons license and will be hosted online in perpetuity. Publication costs of the journal are covered by the collection of article processing charges which are paid by the funder, institution or author of each manuscript upon acceptance. There is no charge for submitting a paper to the journal.

    For general information on Open Access at SAGE please visit the Open Access page or view our Open Access FAQs.

    2. Article Processing Charge (APC)

    If, after peer review, your manuscript is accepted for publication, a one-time article processing charge (APC) is payable. This APC covers the cost of publication and ensures that your article will be freely available online in perpetuity under a Creative Commons license.

    The article processing charge (APC) is USD 1,500.

    *The article processing charge (APC) is payable upon acceptance after peer review and is subject to value added tax (VAT) where applicable. If the paying author/institution is based in the European Union, to comply with European law, VAT must be added to the APC. Providing a VAT registration number will allow an institution to avoid paying this tax, except for UK institutions. Payments can be made in GBP or USD.

    3. What Do We Publish?

    3.1 Aims & Scope

    Before submitting your manuscript to Epigenetic Insights, please ensure you have read the Aims & Scope.

    3.2 Article Types

    All articles will be considered for publication; however, preferential consideration will be given to reports of significant interest to the broad epigenetics community. We also accept papers with negative results. Main article types are as follows: Original Research, Brief Reports, Letters to the Editor, Methods, Review, Mini-Reviews, Editorials, Case Reports and Commentaries. Commentaries, Mini- and full-length reviews are typically invited by the Editor-in-Chief, however, unsolicited work will be considered. Commentaries are invite-only. 

    • Original Research
      Research reports are full length original articles that should present a major scientific breakthrough.

    • Brief Reports
      Brief reports are short, timely articles aimed at providing important, breakthrough data that are not embedded within a complex story. While there are no specific length limitations for Brief Reports, authors are encouraged to keep them concise.
    • Letters to the Editor
      A letter to the Editor is a brief communication that either addresses the contents of a published article,or is a correspondence unrelated to a specific article. Its purpose is to make corrections, provide alternative viewpoints, or offer counter arguments. Avoid logical fallacies and ad hominem attacks. Letters to the Editor must be written in a professional tone and include references to support all claims if appropriate.

      A letter to the Editor unrelated to a specific article should not exceed 500 words or have more than 3 references. A letter to the Editor pertaining to a recently published article or to be published concurrently with an article within the journal should not exceed 800 words or have more than 5 references. If an abstract is included, it will automatically be made the first paragraph. Letters should not include figures or research material. Letters to the editor are not charged an APC.

    • Reviews
      Reviews are intended for a broad audience and therefore should be written with a view to informing readers who are not specialized in that particular field. Please avoid excessive jargon and technical detail. Reviews should capture the broad developments and implications of recent work. They should include an abstract of 150 words and should cite no more than 150 references.
    • Mini-Reviews
      Mini-reviews are brief biographical profiles, historical perspectives, or summaries of developments in fast-moving areas. They must be based on published articles; they may address any subject within the scope of Epigenetic Insights. They should not exceed 3,500 words (excluding the abstract, references and figure and table legends), 4 figures plus tables combined and approximately 40 references.
    • Commentaries
      Commentaries are by invitation only. These are short summaries of significant recent and forthcoming papers, published elsewhere, that provide additional insights, new interpretations or speculation on the relevant topic. These manuscripts may include models, which due to space limitations were not included or discussed in the original paper. Commentary material may be peer reviewed at the Editor's discretion. 
    • Methods and Protocols
      Methods and protocols describe a powerful experiment, a method or important technical updates relevant to the field. The Protocols section only features proven protocols, thus the authors of the protocol must have previously used their method to produce the work reported in a peer-reviewed primary journal.
    • Meeting Report
      This manuscript type reports on a meeting with specific relevance to the journal it is submitted to. Meetings can be international or national conferences or institutional seminars.

    3.3 Writing Your Paper

    The SAGE Author Gateway has some general advice and on how to get published, plus links to further resources.

    3.3.1 Making Your Article Discoverable
    When writing up your paper, think about how you can make it discoverable. The title, keywords and abstract are key to ensuring readers find your article through search engines such as Google. For information and guidance on how best to title your article, write your abstract and select your keywords, have a look at this page on the Gateway: How to Help Readers Find Your Article Online

    4. Editorial Policies

    4.1 Peer Review Policy

    The journal’s policy is to have manuscripts reviewed by two expert reviewers. Epigenetic Insights utilizes a single-blind peer review process in which the reviewer’s name and information is withheld from the author. All manuscripts are reviewed as rapidly as possible, while maintaining rigor. Reviewers make comments to the author and recommendations to the Executive Editor who then makes the final decision.

    The Editor or members of the Editorial Board may occasionally submit their own manuscripts for possible publication in the journal. In these cases, the peer review process will be managed by alternative members of the Board and the submitting Editor / Board member will have no involvement in the decision-making process.

    Epigenetic Insights is committed to delivering high quality, fast peer-review for your paper, and as such has partnered with Publons. Publons is a third party service that seeks to track, verify and give credit for peer review. Reviewers for Epigenetic Insights can opt in to Publons in order to claim their reviews or have them automatically verified and added to their reviewer profile. Reviewers claiming credit for their review will be associated with the relevant journal, but the article name, reviewer’s decision and the content of their review is not published on the site. For more information visit the Publons website.

    4.2 Authorship

    Papers should only be submitted for consideration once consent is given by all contributing authors. Those submitting papers should carefully check that all those whose work contributed to the paper are acknowledged as contributing authors.

    The list of authors should include all those who can legitimately claim authorship. This is all of those who:

    1. Made a substantial contribution to the concept or design of the work; or acquisition, analysis or interpretation of data,
    2. Drafted the article or revised it critically for important intellectual content,
    3. Approved the version to be published,
    4. Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content.

    Authors should meet the conditions of all of the points above. 
    When a large, multicentre group has conducted the work, the group should identify the individuals who accept direct responsibility for the manuscript. These individuals should fully meet the criteria for authorship.

    Acquisition of funding, collection of data, or general supervision of the research group alone does not constitute authorship, although all contributors who do not meet the criteria for authorship should be listed in the Acknowledgments section. Please refer to the International Committee of Medical Journal Editors (ICMJE) authorship guidelines for more information on authorship.

    4.3 Acknowledgements

    All contributors who do not meet the criteria for authorship should be listed in an Acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, or a department chair who provided only general support.

    4.3.1 Writing Assistance
    Individuals who provided writing assistance, e.g. from a specialist communications company, do not qualify as authors and so should be included in the Acknowledgements section. Authors must disclose any writing assistance – including the individual’s name, company and level of input – and identify the entity that paid for this assistance.

    It is not necessary to disclose use of language polishing services.

    Any acknowledgements should appear first at the end of your article prior to your Declaration of Conflicting Interests (if applicable), any notes and your References.

    4.4 Funding

    Epigenetic Insights requires all authors to acknowledge their funding in a consistent fashion under a separate heading.  Please visit the Funding Acknowledgements page on the SAGE Journal Author Gateway to confirm the format of the acknowledgment text in the event of funding, or state that: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. 

    4.5 Declaration of Conflicting Interests                    

    It is the policy of Epigenetic Insights to require a declaration of conflicting interests from all authors enabling a statement to be carried within the paginated pages of all published articles.

    Please ensure that a ‘Declaration of Conflicting Interests’ statement is included at the end of your manuscript, after any acknowledgements and prior to the references. If no conflict exists, please state that ‘The Author(s) declare(s) that there is no conflict of interest’.

    For guidance on conflict of interest statements, please see the ICMJE recommendations.

    4.6 Research Ethics and Patient Consent

    Medical research involving human subjects must be conducted according to the World Medical Association Declaration of Helsinki.

    Submitted manuscripts should conform to the ICMJE Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals, and all papers reporting animal and/or human studies must state in the methods section that the relevant Ethics Committee or Institutional Review Board provided (or waived) approval. Please ensure that you have provided the full name and institution of the review committee, in addition to the approval number.

    For research articles, authors are also required to state in the methods section whether participants provided informed consent and whether the consent was written or verbal.

    Information on informed consent to report individual cases or case series should be included in the manuscript text. A statement is required regarding whether written informed consent for patient information and images to be published was provided by the patient(s) or a legally authorized representative. Please do not submit the patient’s actual written informed consent with your article, as this in itself breaches the patient’s confidentiality. The Journal requests that you confirm to us, in writing, that you have obtained written informed consent but the written consent itself should be held by the authors/investigators themselves, for example in a patient’s hospital record. The confirmatory letter may be uploaded with your submission as a separate file.

    Please also refer to the ICMJE Recommendations for the Protection of Research Participants

    All research involving animals submitted for publication must be approved by an ethics committee with oversight of the facility in which the studies were conducted. The journal has adopted the Consensus Author Guidelines on Animal Ethics and Welfare for Veterinary Journals published by the International Association of Veterinary Editors.

    4.7 Clinical Trials

    Epigenetic Insights conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first patient enrolment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract.

    4.8 Reporting Guidelines

    The relevant EQUATOR Network reporting guidelines should be followed depending on the type of study. For example, all randomized controlled trials submitted for publication should include a completed CONSORT flow chart as a cited figure and the completed CONSORT checklist should be uploaded with your submission as a supplementary file. Systematic reviews and meta-analyses should include the completed PRISMA flow chart as a cited figure and the completed PRISMA checklist should be uploaded with your submission as a supplementary file. The EQUATOR wizard can help you identify the appropriate guideline.

    Other resources can be found at NLM’s Research Reporting Guidelines and Initiatives.

    5. Publishing Policies

    5.1 Publication Ethics

    SAGE is committed to upholding the integrity of the academic record. We encourage authors to refer to the Committee on Publication Ethics’ International Standards for Authors and view the Publication Ethics page on the SAGE Author Gateway.

    5.1.1 Plagiarism

    Epigenetic Insights and SAGE take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. We seek to protect the rights of our authors and we always investigate claims of plagiarism or misuse of published articles. Equally, we seek to protect the reputation of the journal against malpractice. Submitted articles may be checked with duplication-checking software. Where an article, for example, is found to have plagiarized other work or included third-party copyright material without permission or with insufficient acknowledgement, or where the authorship of the article is contested, we reserve the right to take action including, but not limited to: publishing an erratum or corrigendum (correction); retracting the article; taking up the matter with the head of department or dean of the author's institution and/or relevant academic bodies or societies; or taking appropriate legal action.

    5.1.2 Prior Publication

    If material has been previously published, it is not generally acceptable for publication in a SAGE journal. However, there are certain circumstances where previously published material can be considered for publication. Please refer to the guidance on the SAGE Author Gateway or if in doubt, contact the Editor at the address given below.

    5.2 Contributor’s Publishing Agreement

    Before publication SAGE requires the author as the rights holder to sign a Journal Contributor’s Publishing Agreement. Epigenetic Insights publishes manuscripts under Creative Commons licenses. The standard license for the journal is Creative Commons by Attribution Non-Commercial (CC BY-NC), which allows others to re-use the work without permission as long as the work is properly referenced and the use is non-commercial. For more information, you are advised to visit SAGE's OA licenses page.

    Alternative license arrangements are available, for example, to meet particular funder mandates, made at the author’s request.

    6. Preparing Your Manuscript

    6.1 Word Processing Formats

    The preferred format for your manuscript is Word. LaTeX files are also accepted. Word and
    (La)Tex templates are available on the Manuscript Submission Guidelines page of our Author

    6.2 Artwork, Figures and other Graphics

    For guidance on the preparation of illustrations, pictures and graphs in electronic format, please
    visit SAGE’s Manuscript Submission Guidelines.

    Figures supplied in color will appear in color online.

    6.3 Supplemental Material

    This journal is able to host additional materials online (e.g. datasetsm podcasts, videos, images etc.) alongside the full-text of the article. These will be subjected to peer-review alongside the article. For more information please refer to our guidelines on submitting supplemental files, which can be found within our Manuscript Submission Guidelines page.  

    6.4 Reference Style

    Epigenetics Insights adheres to the AMA reference style (this site requires a subscription). Please review the guidelines on AMA to ensure your manuscript conforms to this reference style.

    If you use Endnote to manage references, you can download the AMA output file here.

    6.5 English Language Editing Services

    Authors seeking assistance with English language editing, translation, or figure and manuscript formatting to fit the journal’s specifications should consider using SAGE Language Services. Visit SAGE Language Services on our Journal Author Gateway for further information.

    7. Submitting your Manuscript

    7.1 How to Submit your Manuscript

    Visit our Peer Review Site to login and submit your article online. Please ensure that references are formatted with the AMA reference style.

    7.2 Title, Keywords and Abstracts

    Please supply a title, short title, an abstract and keywords to accompany your article. The title,
    keywords and abstract are key to ensuring readers find your article online through online search
    engines such as Google. Please refer to the information and guidance on how best to title your
    article, write your abstract and select your keywords by visiting the SAGE Journal Author
    Gateway for guidelines on How to Help Readers Find Your Article Online. 

    7.3 Information Required for Completing your Submission

    You will be asked to provide contact details and academic affiliations for all co-authors via the submission system and identify who is to be the corresponding author. These details must match what appears on your manuscript. The affiliation listed on the manuscript should be the institution where the research was conducted. If an author has moved to a new institution since completing the research, the new affiliation can be included in a manuscript note at the end of the paper. At this stage please ensure you have included all the required statements and declarations and uploaded any additional supplementary files (including reporting guidelines where relevant).

    7.4 ORCID

    As part of our commitment to ensuring an ethical, transparent and fair peer review process SAGE is a supporting member of ORCID, the Open Researcher and Contributor ID. ORCID provides a persistent digital identifier that distinguishes researchers from every other researcher and, through integration in key research workflows such as manuscript and grant submission, supports automated linkages between researchers and their professional activities ensuring that their work is recognized.

    All authors must add their ORCIDs to their SAGE Track accounts and include their ORCIDs as part of the submission process. If you don’t already have one you can create one here or visit our ORCID homepage to learn more.

    7.5 Permissions

    Authors are responsible for obtaining permission from copyright holders for reproducing any illustrations, tables, figures or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please visit our Frequently Asked Questions on the SAGE Journal Author Gateway.

    8. On Acceptance and Publication

    If your paper is accepted for publication after peer review, you will first be asked to complete the contributor’s publishing agreement. Once your manuscript files have been checked for SAGE Production, the corresponding author will be asked to pay the article processing charge (APC) via a payment link. Once the APC has been processed, your article will be prepared for publication and can appear online within an average of 30 days. Please note that no production work will occur on your paper until the APC has been received.

    8.1 SAGE Production

    Your SAGE Production Editor will keep you informed as to your article’s progress throughout the production process. Proofs will made available to the corresponding author via our editing portal SAGE Edit, or by email to the corresponding author and should be returned promptly.  Authors are reminded to check their proofs carefully to confirm that all author information, including names, affiliations, sequence and contact details are correct, and that Funding and Conflict of Interest statements, if any, are accurate. Please note that if there are any changes to the author list at this stage all authors will be required to complete and sign a form authorizing the change.

    8.2 Online Publication

    One of the many benefits of publishing your research in an open access journal is the speed to publication. With no page count constraints, your article will be published online in a fully citable form with a DOI number as soon as it has completed the production process. At this time it will be completely free to view and download for all.

    8.3 Promoting Your Article

    Publication is not the end of the process! You can help disseminate your paper and ensure it is as widely read and cited as possible. The SAGE Author Gateway has numerous resources to help you promote your work. Visit the Promote Your Article page on the Gateway for tips and advice. In addition, SAGE is partnered with Kudos, a free service that allows authors to explain, enrich, share, and measure the impact of their article. Find out how to maximize your article’s impact with Kudos.

    9. Further Information

    Any correspondence, queries or additional requests for information on the Manuscript Submission process should be sent to the Epigenetic Insights editorial office as follows:

    Barbara Rattner, PhD | Executive Editor |